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As an interdisciplinary artist, educator, and poet, Keefer uses painting, drawings, and time-based media to interrogate issues related to how we experience memory, migration, and trauma as location specific.  Using an expanded documentary format, Keefer bears witness to overlapping and conflicting human and animal kinship systems, the site-based nature of memory, and how we tell stories to make sense of  chaos. Through her fieldwork, she situates her installations and maps gray areas within categories seen as binary, such as urban/rural, domestic/wild, trauma/safety, or family/individual.
 
Influences include Kiki Smith, Donna Haraway, William Kentridge, and Anselm Kiefer.
 
Keefer recieved a BFA in Painting and Drawing and an MA in Art Museum Education from the University of North Texas, and holds an MFA in Media Art from Southern Illinois University, Carbondale.

Keefer has been a Teaching Artist throughout her career, first at museums including the Art Institute of Chicago and the Dallas Museum of Art, then at K-12 schools in Texas and Massachusetts. Currently, Keefer teaches at the University of Missouri, St. Louis and at Southwestern Illinois College.

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